How to say hypothetically, 仮に & 仮定で?

Idk how to explain "hypothetical" to a japanese friend. I want to say "hypothetically if i ran 5 miles right now id get really thirsty"

Could i use kari ni/ katei de? For example

今5マイル走ると仮定したら、のどがすごくかわってくるだろう

Or 仮に今5マイル走ったらのどがすごくかわってくるだろう

Im pretty confused, not sure if i should use moshikashite or which tense of kawaru etc

Thanks! I need lots of explanation

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