Was it possible to have our biological baby after …?

It was nearly six years since we married (me and my wife). After two years of our married she was pregnant but failed to give a birth due to unexpected rise in her pressure while she was eight month pregnant. Since then we tried to have another but failed to do so. Her cycle is rarely appearing possibly at two or three months intervals and also in two weeks interval (though it is only once). This day she has never seen any cycle for the last four months. We have consulted our physician, one of the best physicians in the country where we are living, several times. he tried all his best including fertility treatment (injection) but not successful. We are very eager to have our biological baby. This issue disturbs us seriously, particularly frustration come to my wife. I raise issues like adopting but she strongly resists me. Now I am 39 and she is 40 and we love each other. How can we have our biological baby after ….? Is there any one who had such experience? Are there technologies that really help us? Please…. please help us……..

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