If L1 intersects L2, then their x-, y-, and z-coordinates must match. So we must have
x: 5 + 5s = 2 + 8t
y: 1 = 4 - 3t
z: 4 + 2s = 5 + 2t
or after some rearrangement,
5s - 8t = -3
3t = 3
2s - 2t = 1
The second equation immediately gives us t = 1. Putting this in the first equation and solving for s, we get s = 1. But s = 1, t = 1 does not satisfy the last equation. So L1 and L2 have no point of intersection.
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If L1 intersects L2, then their x-, y-, and z-coordinates must match. So we must have
x: 5 + 5s = 2 + 8t
y: 1 = 4 - 3t
z: 4 + 2s = 5 + 2t
or after some rearrangement,
5s - 8t = -3
3t = 3
2s - 2t = 1
The second equation immediately gives us t = 1. Putting this in the first equation and solving for s, we get s = 1. But s = 1, t = 1 does not satisfy the last equation. So L1 and L2 have no point of intersection.